How Can A Margarita Do This?

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Sam’s friend got a crazy swelling, peeling burn on her hands from making a margarita and then heading to the beach. Why? #margaritaburn #margarita #phytophotodermatitis

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Credits:
Producer: Andrew Sobey

Writer/Host: Samantha Jones, PhD

Executive Producers:
George Zaidan
Hilary Hudson

Scientific Consultants:
Leila Duman, PhD
Frank Gasparro, PhD
Jeremy Goverman, MD
Tien Nguyen, PhD
Brianne Raccor, PhD

SOURCES
The Distribution of Coumarins and Furanocoumarins in Citrus Species Closely Matches Citrus Phylogeny and Reflects the Organization of Biosynthetic Pathways
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641707/

Psoralen Derivatives with Enhanced Potency
https://onlinelibrary.wiley.com/doi/abs/10.1111/php.13263

Phytophotodermatitis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772689/

Lime-induced phytophotodermatitis
https://academic.oup.com/omcr/article/2019/11/470/5670819

Burned by a Margarita
https://www.theatlantic.com/science/archive/2016/07/burned-iby-a-margarita/492149/

Fig tree induced phytophotodermatitis
https://casereports.bmj.com/content/13/3/e233392.long

Chemistry and health effects of furanocoumarins in grapefruit
https://www.sciencedirect.com/science/article/pii/B9780444634306000059

Psoralen
https://www.ncbi.nlm.nih.gov/books/NBK547880/

Margarita Photodermatitis
https://www.nejm.org/doi/full/10.1056/NEJM199303253281220

The Nature and Molecular Basis of Cutaneous Photosensitivity Reactions to Psoralens and Coal Tar
https://pubmed.ncbi.nlm.nih.gov/6854058/

Risk and Progression Factors in Carcinogenesis [Psoralen Photobiology]
https://www.springer.com/gp/book/9783642643859

Mexican Beer Dermatitis: Scourge Of The Beach Bum And The Proper Lady
https://www.npr.org/sections/health-shots/2010/10/21/130722086/mexican-beer-dermititus-the-scourge-of-the-beach-bum

Mexican Beer Dermatitis: A Unique Variant of Lime Phytophotodermatitis Attributable to Contemporary Beer-Drinking Practices
https://jamanetwork.com/journals/jamadermatology/article-abstract/422062

Polyphenols and Polyphenol-Derived Compounds From Plants and Contact Dermatitis
https://www.sciencedirect.com/science/article/pii/B9780128130087000291#:~:text=Polyphenols%20and%20polyphenol%2Dderived%20compounds%20from%20plants%20are%20common%20causes,%2C%20and%2For%20irritant%20dermatitis.&text=Most%20contact%20allergens%20of%20polyphenol,to%20quinones%20in%20the%20skin.

Phytophotodermatitis: the other "lime" disease
https://pubmed.ncbi.nlm.nih.gov/10195477/

Chemistry in Pictures: Club Med dermatitis
https://cen.acs.org/safety/Chemistry-Pictures-Club-Med-dermatitis/98/web/2020/07

Treating phytophotodermatitis
https://newsnetwork.mayoclinic.org/discussion/sun-related-skin-condition-triggered-by-chemicals-in-certain-plants-fruits/#:~:text=To%20prevent%20phytophotodermatitis%2C%20wash%20your,skin%20that%20weren’t%20covered.

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